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Exosomes — Taking Microneedling to the Next Level

Jul 07, 2025

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Exosomes — Taking Microneedling to the Next Level

Modern medicine is shifting toward regeneration, which is a far more sustainable approach to great health. A fine example of this is microneedling with exosomes, which rebuilds your skin’s support.

Different eras and advances in modern medicine can radically change how we approach health and wellness. Today, the era is one of regeneration — instead of focusing on fixing, we’re aiming more toward rebuilding, which can deliver far superior results.

Regenerative medicine is being embraced in practically every medical field, including dermatology. And when regenerative science meets skin care, the results are impressive.

A great example of this is the use of exosomes during microneedling, a powerful skin rejuvenation treatment that Dr. Samantha Robare and the team here at Magnolia Dermatology are thrilled to offer.

"Microneedling with exosomes has truly impressed me. I had considered fillers as I started losing volume with age, but this treatment gave my skin a noticeable glow and overall improvement, with minimal downtime. I love how it refreshes my whole face!" - Diana Chou, Physician Assistant at Magnolia Dermatology

Here’s a look at how microneedling with exosomes delivers a powerful regenerative punch that can refresh aging and tired skin.

What are exosomes?

Let’s first dive into a little science and explain our use of exosomes. Very briefly, exosomes are nano-sized extracellular vesicles that contain proteins, lipids, and nucleic acids. Exosomes are found in almost all of your cells, which use them as messengers between cells.

When it comes to how these tiny messengers can help to rebuild skin, we’ll turn to a recent study that researched the effects of exosomes in reversing photoaging in skin. 

What researchers found is impressive — exosomes help skin fight back against collagen and elastin loss, oxidative stress, and inflammation. They do this by signaling your body to send in regenerative resources — for example, the proteins signal for more collagen and elastin production.

Microneedling — an excellent collagen induction therapy

Now let’s move over to the second piece of this skin regeneration puzzle — microneedling. We’re pleased to offer SkinPen® microneedling, which is a leading technology.

With SkinPen, we create a matrix of micro-channels across the surface of your skin to elicit a mild healing response. Your body’s healing response is a regenerative one, and there are four stages:

  1. Hemostasis — blood vessel constriction
  2. Inflammation — creating a healing environment
  3. Cell proliferation
  4. Remodeling

When we create microchannels with SkinPen, your body initiates a cascade of growth factors that call on regenerative resources, such as collagen and elastin.

Not only does microneedling help create new collagen and elastin support from below to tighten sagging skin, but it can also break up surface concerns, such as age spots and facial veins.

Adding exosomes to microneedling for a powerful boost

When we add exosomes to your SkinPen microneedling procedure, we’re making an already fantastic skin treatment even better. With the addition of exosomes, we enhance the regenerative capacity of your skin, providing a faster and more effective response that resets your aging skin.

So, if you want to dial back the damage in your skin and make it glow with great health again, it’s a very good idea to put microneedling with exosomes into your skin care rotation.

To learn more or to schedule your microneedling with exosome treatment, please contact us at Magnolia Dermatology in Cypress, Texas.